The International GCE Webinar is a monthly webinar series, open to all, featuring talks on cutting-edge applications of genetic code expansion (GCE) technologies as well as advances in the GCE field. It is organized by the Oregon State University GCE4All Research Center and hosted by Rick Cooley and John Lueck. The webinar is meant to be of value to both developers and users of GCE, as well as anyone interested in learning more about it. Speakers will be from around the globe, and we invite speaker and topic suggestions.
International GCE Webinar
Webinar mechanics
The webinars run from October through June and occur on the third Thursday of each month at 10 a.m. Eastern Time (corresponding to 2 p.m. GMT March-October and 3 p.m. GMT November through February). The general format is to give each of the two speakers 30 minutes which we recommend be divided into a presentation of 20-25 minutes followed by 5-10 minutes of discussion.
Registration
When possible, seminars will be recorded and made available for viewing on the GCE4All YouTube Channel; as this will not be possible for all seminars, please make it a priority to register for and participate in the live events. Although the seminars are free and open to all, pre-registration is required to get the specific link for each seminar.
Register here
Check out our YouTube Channel
Upcoming Webinars
April 20th, 2023
TBD
Andrea Cochran (Genentech, Inc.)
Split aminoacyl-tRNA synthetases for proximity-induced stop codon suppression
Jeffery M. Tharp (Indiana University School of Medicine)
The ability to control gene expression in living cells has many useful applications in biotechnology and medicine. In this talk I will describe the design and engineering of split orthogonal aminoacyl-tRNA synthetases (o-aaRSs) that can be used to tightly control gene expression in bacteria and in human cells. Furthermore, I will describe how these split o-aaRSs can serve as useful tools for detecting protein–protein interactions, including those involved human disease.
May 18th, 2023
TBD
Sharona Gordon (University of Washington)
Fluorescent Amino Acid Method Development
James Petersson (University of Pennsylvania)
June 15th, 2023
F-NMR with Fluorinated Amino Acids
Angela Gronenborn (University of Pittsburgh)
TBD
Jiangyun Wang (University of Chinese Academy of Sciences)
Past Webinars
October 20th, 2022
A Journey from In Vitro Misacylated tRNAs to Yeast Synthetic Biology
Virginia Cornish (Columbia University)
PermaPhos: Revealing New Functions of Phosphorylated Proteins (Recording)
Rick Cooley (Oregon State University)
November 17th, 2022
Genetically encoded chemical tools for protein studies in the live cell (Recording)
Irene Coin (Leipzig)
Design and Evolution of Enzymes with Non-Canonical Catalytic Mechanisms (Recording)
Anthony Green (Manchester, UK)
December 15th, 2022
Investigations of multi-domain DNA/RNA binding protein machines using FEncAA (Recording)
Edwin Antony (Saint Louis University, School of Medicine)
Decoding the Language of Aromatic Side-Chains in Ion Channels and Receptors (Recording)
Chris Ahern (University of Iowa)
January 19th, 2023
How to make a thermostable ribosome
Jamie H. D. Cate (University of California, Berkeley)
Methodological challenges of an expanded genetic code (Recording)
Nediljko Budisa (University of Manitoba, Canada)
February 16th, 2023
Engineering Biomaterials Bearing Non-Canonical Amino Acids (Recording)
Jin Kim Montclare (New York University)
Expanded genetic code for live-cell fluorescent protein labeling in (neuro)biology (Recording)
Ivana Nikic-Spiegel (Tuebingen)
March 16th, 2023
Identification of neuropeptide and toxin binding sites on a membrane-embedded receptor through crosslinking (Recording)
Stephan Pless (University of Copenhagen)
Expanding the genetic code – new chemistries for biology
Kathrin Lang (ETH Zurich)
GCE Community Networking
A resource available for more extensive discussion and networking among those learning about, using and/or developing GCE technologies is the GCE bulletin board – GCEbb – a forum for email-based discussions. More information about the GCEbb, including how to join the email list, can be found at the GCEbb home page. We are looking forward to having you join our GCE conversations!